Histidine decarboxylase and urinary methylimidazoleacetic acid in gastric neuroendocrine cells and tumours
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چکیده
منابع مشابه
Histidine decarboxylase and urinary methylimidazoleacetic acid in gastric neuroendocrine cells and tumours.
AIM To study histidine decarboxylase (HDC) expression in normal and neoplastic gastric neuroendocrine cells in relationship to the main histamine metabolite. METHODS Control tissues from fundus (n = 3) and corpus (n = 3) mucosa of six patients undergoing operations for gastric adenocarcinoma, biopsy and/or gastric surgical specimens from 64 patients with primary gastric neuroendocrine tumours...
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BACKGROUND Gastric neuroendocrine tumours (NETs) are increasingly recognised, and management decisions may be difficult due to an incomplete understanding of aetiology, natural history and optimum therapy. This article presents a current understanding based on recent advances in epidemiology, classification, molecular profiling, and treatment. METHODS Relevant medical literature was identifie...
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1 Saverymuttu SH, Peters AM, Lavender PJ, Hodgson HJ, Chadwick VS. "'Indium autologous leucocytes in inflammatory bowel disease. Gut 1983; 24: 293-9. 2 Bernstein J. Colonic ulceration and bleeding during diclofenac therapy. N Engl J Med 1990; 323: 135. 3 Bjarnason I, Price AB. Effect of NSAID on the large bowel. GI Futures and Clin Pract 1988; 3: 7-10. 4 Rampton DS. NSAID and the lower gastroin...
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Histidine decarboxylase (HDC) represents the sole enzyme that produces histamine in the body. The present work investigated the role of endogenous histamine in carbachol- and gastrin-induced gastric acid secretion with HDC-knockout (HDC-/-) mice. Acid secretion was measured in either mice subjected to acute fistula production under urethane anesthesia or conscious mice that had previously under...
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ژورنال
عنوان ژورنال: World Journal of Gastroenterology
سال: 2015
ISSN: 1007-9327
DOI: 10.3748/wjg.v21.i47.13240